Acyl bromides
Medchemexpress LLC Demecarium bromide | 56-94-0 | MFCD00152376 | 95.0% | 716.59 | C32H52Br2N4O4 | 10 MG
Demecarium bromide is a long-acting quaternary ammonium cholinesterase inhibitor used in research on glaucoma and cholinesterase activity. Supplied as the bromide salt, it has a reported apparent affinity (Kiapp) of approximately 0.15 μM and is provided with a product data sheet and SDS for safe handling.
- Long-acting cholinesterase inhibitor for glaucoma research
- Reported Kiapp ~0.15 μM against cholinesterase
- High chemical purity (~95.0%) suitable for research use
- Available in small quantities for laboratory experiments
- Provided with a product data sheet and safety data sheet
Selleck Chemical LLC Aclidinium Bromide S4031-10mg
Aclidinium Bromide (LAS 34273 LAS-W 330) inhibits human muscarinic AChR M1 M2 M3 M4 and M5 with Ki of 0 1 nM 0 14 nM 0 14 nM 0 21 nM and 0 16 nM respectively
Selleck Chemical LLC Pinaverium bromide
Pinaverium bromide (Icosapentaenoic acid) acts as a calcium channel blocker and is useful for functional gastrointestinal disorders
Selleck Chemical LLC Domiphen Bromide S4186-50mg
Domiphen bromide (NSC-39415) is a quaternary ammonium antiseptic with actions as a cationic surfactant
Apexbio Technology LLC Tiotropium Bromide hydrate 139404-48-1 50mg
Tiotropium Bromide hydrate is a small-molecule antagonist targeting muscarinic acetylcholine receptors (mAChRs) It is designed to competitively inhibit mAChRs thereby modulating airway smooth muscle contraction and mediating bronchodilation Tiotropium Bromide hydrate exerts its biological activity primarily through competitive antagonism at mAChRs resulting in relaxation of airway smooth muscle Based on these pharmacological properties Tiotropium Bromide hydrate holds research potential in respiratory pharmacology particularly for investigating mechanistic pathways in chronic obstructive pulmonary disease (COPD) receptor-ligand interactions and pulmonary pharmacodynamics associated with airway obstruction
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 508.49 | 250 MG
Umeclidinium bromide is a novel mAChR antagonist with high affinity for cloned human M1-M5 mAChRs. It exhibits slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus. It also inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells.
- Target: mAChR
- Pathway: GPCR/G protein, neuronal signaling
- Inhibits human ether-a-go-go-related gene channel tail current
- Demonstrates slow functional reversibility at M3 mAChRs
Medchemexpress LLC Bromoacetyl-PEG3-DBCO | 00-00-0 | 98.6% | C29H34BrN3O6 | 10MG
Bromoacetyl-PEG3-DBCO is a heterobifunctional PEG linker containing a dibenzocyclooctyne (DBCO) moiety and a bromoacetyl reactive handle. It is designed for conjugation and linker installation in PROTAC and bioconjugation workflows, enabling click chemistry and selective nucleophile coupling.
- Facilitates SPAAC via a strained alkyne DBCO group.
- Provides a bromoacetyl handle for selective conjugation to thiols or amines.
- PEG3 spacer improves solubility and reduces steric hindrance.
- High purity suitable for research and synthesis workflows.
- Available in small-scale pack sizes for discovery chemistry.
Apexbio Technology LLC Cetrimonium Bromide (CTAB) 57-09-0 100mg
Cetrimonium Bromide (CTAB) (CAS 57-09-0) is a cationic surfactant that exerts its biological activity primarily through disruption of microbial membrane integrity via electrostatic interactions with negatively charged membrane components CTAB demonstrates antimicrobial activity by inhibiting microbial growth in in vitro assays Commonly employed in molecular biology protocols CTAB facilitates nucleic acid extraction through cellular lysis precipitation and purification particularly in plant genomic DNA isolation Additionally it is useful for antiseptic formulation studies nanoparticle synthesis and pharmaceutical research including drug delivery system development and stability studies
Aobchem Tetradecylammonium bromide | ≥95% | CAS 14937-42-9 | 25g
Tetradecylammonium bromide | ≥95% | CAS 14937-42-9 | 25g
Aobchem 5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 10g
5-Benzoyl-2-thiophenecarboxaldehyde | 95% | CAS 72157-21-2 | C12H8O2S | 10g
Medchemexpress LLC Rocuronium Bromide (ORG 9426 Bromide) | 119302-91-9 | 98.0% | 609.68 | 5 MG
Rocuronium Bromide is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is intended for research use only.
- Aminosteroid non-depolarizing neuromuscular blocker
- Muscle relaxant
- Used in modern anaesthesia
- Facilitates endotracheal intubation
- Provides skeletal muscle relaxation during surgery or mechanical ventilation
- For research use only
Medchemexpress LLC Domiphen bromide | 538-71-6 | 98.7% | 1 ML
Domiphen bromide is a cationic active quaternary ammonium salt that inhibits HERG channels, aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. It exhibits antibacterial, antimalarial, and disinfectant properties, and acts as a synergist for Colistin. This compound can be utilized as a chemical preservative and cationic surfactant, and is also relevant for research into bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
- Cationic active quaternary ammonium salt
- Inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin
- Antibacterial, antimalarial, and disinfectant properties
- Synergist of colistin
- Can be used as a chemical preservative and cationic surfactant
- Applicable in research of bacterial infectious diseases like pharyngitis, thrush, and oral ulcers
Apexbio Technology LLC Umeclidinium bromide 869113-09-7 2mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
Medchemexpress LLC Fentonium bromide | 5868-06-4 | 98.8% | 25MG
Fentonium bromide | 5868-06-4 | 98.8% | 25MG