Acyl bromides
Medchemexpress LLC Mepenzolate bromide | 76-90-4 | 99.9% | 420.34 | 100 MG
Mepenzolate bromide is an orally administered muscarinic receptor antagonist with Kis of 0.68 and 2.6 nM for hM2R and hM3R, respectively. It can be used to suppress gastrointestinal hypermotility associated with irritable bowel syndrome. Mepenzolate bromide is also a GPR109A inhibitor.
- Muscarinic receptor antagonist
- GPR109A inhibitor
- Exerts anti-inflammatory effect via a muscarinic receptor-independent mechanism
- Bronchodilatory effect via a muscarinic receptor-dependent mechanism
- Subtype-non-specific muscarinic antagonist
- Beneficial effects in a mouse model of chronic obstructive pulmonary disease (COPD)
Medchemexpress LLC Aclidinium (Bromide) | 320345-99-1 | C26H30BrNO4S2 | 100 MG
Aclidinium (Bromide) | 320345-99-1 | C26H30BrNO4S2 | 100 MG
TARGETMOL CHEMICALS INC Sofpironium bromide 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. Purity 98.04%
Medchemexpress LLC Ipratropium bromide hydrate | 66985-17-9 | 99.9% | 500 MG
Ipratropium bromide hydrate is a muscarinic receptor antagonist that relaxes smooth muscle. It can be used in research for COPD (chronic obstructive pulmonary disease) and asthma.
- Muscarinic receptor antagonist
- IC50s of 2.9 nM for M1, 2 nM for M2, and 1.7 nM for M3 receptors
- Exerts toxic effects via disruption of mitochondrial membrane potential
- Increases infarct size in isolated perfused heart ischaemia/reperfusion experiments with a dose-responsive manner
- Inhibits adult rat cardiac myocyte growth after hypoxia treatment
Medchemexpress LLC Rocuronium bromide | 119302-91-9 | MFCD00867768 | 98.0% | 609.68 g/mol | C32H53BrN2O4 | 10 MG
Rocuronium bromide is an aminosteroid, non-depolarizing neuromuscular blocking agent supplied as a white to off-white solid for laboratory research use. It is commonly used to study nicotinic acetylcholine receptor interactions and neuromuscular transmission in vitro. This material is intended for research purposes only and is not for clinical, diagnostic, or therapeutic use.
- Purity approximately 98.0%.
- White to off-white solid appearance.
- Molecular weight 609.68 g/mol.
- Soluble in DMSO and water (≈100 mg/mL); ultrasonic may be required.
- Store solid at 4°C; store solutions at -80°C (up to 6 months) or -20°C (up to 1 month) when sealed.
- Provided in milligram quantities suitable for laboratory assays.
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 5.9 MG
Pinaverium bromide is an L-type calcium channel blocker that selectively targets the gastrointestinal tract. It is effective in relieving pain, diarrhea, and intestinal discomfort, providing therapeutic benefits for patients with Irritable Bowel Syndrome (IBS) without significant adverse effects.
- L-type calcium channel blocker
- Gastrointestinal selectivity
- Symptom relief for pain, diarrhea, and intestinal discomfort
- Therapeutic for Irritable Bowel Syndrome patients
- Favorable safety profile
eMolecules 4-(Bromoacetyl)pyridine hydrobromide | Combi-Blocks | 5349-17-7 | MFCD02681893 | 280.947 | C7H7Br2NO | 90.000 | Br.BrCC(=O)c1ccncc1 | 5g | 249357428
4-(Bromoacetyl)pyridine hydrobromide | Combi-Blocks | 5349-17-7 | MFCD02681893 | 280.947 | C7H7Br2NO | 90.000 | Br.BrCC(=O)c1ccncc1 | 5g | 249357428
Medchemexpress LLC Vecuronium bromide | 50700-72-6 | MFCD00867762 | 99.9% | 100 MG
Vecuronium bromide is a non-depolarizing neuromuscular blocking agent. It also functions as a nicotinic acetylcholine receptor (nAChR) inhibitor and a muscle relaxant. This compound can be used for pre-surgical anesthesia and is intended for research use only.
- Non-depolarizing neuromuscular blocking agent
- Inhibits nicotinic acetylcholine receptors (nAChR)
- Acts as a muscle relaxant
- Can be used for pre-surgical anesthesia
- Suitable for research applications only
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 5 MG
Cimetropium Bromide (DA-3177) is a mAChR antagonist used for the long-term treatment of irritable bowel syndrome.
Medchemexpress LLC Cimetropium Bromide | 51598-60-8 | 438.36 | 10 MM * 1 ML
Cimetropium Bromide (DA-3177) is an mAChR antagonist developed for the long-term treatment of irritable bowel syndrome. This compound is intended for research use only and functions as a competitive antagonist of muscarinic-mediated contractions in isolated colonic preparations.
- Acts as a competitive antagonist of muscarinic-mediated contractions.
- Exhibits potent antimuscarinic effects on longitudinal muscle preparations.
- Effectively inhibits large bowel motility in vivo.
- Suitable for research applications related to irritable bowel syndrome.
Medchemexpress LLC Methyl-PEG3-bromide 25g
Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Rapacuronium bromide (Org 9487) | 156137-99-4 | 98.0% | 677.80 | 25 MG
Rapacuronium bromide (Org 9487) is a non-depolarizing neuromuscular blocker and an allosteric modulator of muscarinic acetylcholine receptor (mAChR). It is for research use only and not sold to patients.
- Non-depolarizing neuromuscular blocker
- Allosteric modulator of muscarinic acetylcholine receptor (mAChR)
Medchemexpress LLC (R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose | 6612-91-5 | 95.1% | 294.30 | 1 ML
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms associated with this process include inhibition of DNA synthesis and induction of apoptosis.
- Appearance: solid
- Color: white to off-white
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: powder: -20°C for 3 years, 4°C for 2 years; in solvent: -80°C for 6 months, -20°C for 1 month
- Purine nucleoside analog
- Broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.